It is increasingly clear that chromatin is not just a device for packing DNA within the nucleus but also a dynamic material that changes as cellular environments alter. The precise control of chromatin modification in response to developmental and environmental cues determines the correct spatial and temporal expression of genes. Here, we review exciting discoveries that reveal chromatin participation in many facets of plant development. These include: chromatin modification from embryonic and meristematic development to flowering and seed formation, the involvement (...) of DNA methylation and chromatin in controlling invasive DNA and in maintenance of epigenetic states, and the function of chromatin modifying and remodeling complexes such as SWI/SNF and histone acetylases and deacetylases in gene control. Given the role chromatin structure plays in every facet of plant development, chromatin research will undoubtedly be integral in both basic and applied plant biology. BioEssays 24:234–243, 2002. © 2002 Wiley Periodicals, Inc.; DOI 10.1002/bies.10055. (shrink)

Kenneth Kipnis (2006) presents a normative defense of strict confidentiality, but it follows from an empirical claim that allowing breach would result in all parties being worse off, including, par...

A student's future as a knowledge worker (one who "thinks for a living" with the task of problem solving) is the starting point of this book. With this in mind, the book combines a review of philosophical positions and problems with practical examples and perspectives gained from everyday challenges faced by knowledge workers in their businesses and organizations. Through the use of summative chapters, highlighted key concepts, questions for reflection, and illustrative examples on how to work with the theories presented, (...) the book provides a clear and accessible introduction to this challenging subject. Philosophy of Science primarily addresses students studying language, communication, marketing, economics, and management. However, the survey of the theoretical schools of thought - as well as the discussions on research ethics and the role of research in society - will be equally relevant for other students in the humanities and the natural and social sciences. (shrink)

La menzogna è irrinunciabile per vincere in politica? Davi ci spiega quali sono i meccanismi di persuasione a cui ricorrono taluni politici per farsi eleggere e quali le responsabilità di quegli elettori che scelgono comunque di votare chi sostiene anche ciò che non può essere vero. È indubbio che la comunicazione politica si rifaccia al simbolismo e al linguaggio delle favole; non necessariamente per occultare la realtà, ma più direttamente per esprimere con maggiore efficacia il suo messaggio. Alle celebri favole (...) di 'Biancaneve', 'Cenerentola', 'Il brutto anatroccolo' sono ricorsi infatti uomini politici del calibro di Berlusconi, Prodi, Nixon, Carter, Mitterrand e partiti quali la Democrazia Cristiana; l'hanno fatto per conquistare voti ma anche per attivare ampi meccanismi di consenso che attingessero direttamente dall'inconscio collettivo. Le conseguenze - ammonisce l'autore - possono essere molto serie, come nel caso dell'attuale politica americana che ha portato la manipolazione e l'inganno a essere riconosciuti come tratti identitari della presidenza di George W. Bush. (shrink)

The question that this paper tries to answer is Q: “Can good academic bioethics be done without commitment to moral theory?” It is argued that the answer to Q is an unequivocal “Yes” for most of what we could call “critical bioethics,” that is, the kind of bioethics work that primarily criticizes positions or arguments already in the literature or put forward by policymakers. The answer is also “Yes” for much of empirical bioethics. The second part of the paper then (...) provides an analysis of Q in relation to “constructive bioethics,” that is, bioethics work aimed at providing an argument for a particular position. In this part, it is argued that a number of the approaches or methods used that initially look like they involve no commitment to moral theory, nevertheless, involve such a commitment. This is shown to be the case for reflective equilibrium, mid-level theory, the use of theory fragments, and argument by analogy. (shrink)

Finding the heart of God -- Finding God's heart -- Have you seen God's face? -- Why does God sing? -- Searching God's mind -- When God is silent -- Did you know God thinks about you? -- God has unique plans for every unsaved person -- God remembers no longer -- Did you know God reads and writes? -- The unknowable of God -- God whispers -- DoesGod have a nose? -- Wax in God's ears -- God loves to (...) provide for our needs -- God's eyes see all -- What God hates -- God heals protectively -- A laughing God -- A tired Jesus -- What angers God? -- God is love -- The holiness of God -- God is good -- God is person -- God is the all-powerful God -- God is all-knowing -- God is everywhere present -- God is spirit -- God does not change -- The Trinity three in one. (shrink)

Western philosophers have traditionally concentrated on theory as the means for expressing knowledge about a variety of phenomena. This absorbing book challenges this fundamental notion by showing how objects themselves, specifically scientific instruments, can express knowledge. As he considers numerous intriguing examples, Davis Baird gives us the tools to "read" the material products of science and technology and to understand their place in culture. Making a provocative and original challenge to our conception of knowledge itself, _Thing Knowledge _demands that (...) we take a new look at theories of science and technology, knowledge, progress, and change. Baird considers a wide range of instruments, including Faraday's first electric motor, eighteenth-century mechanical models of the solar system, the cyclotron, various instruments developed by analytical chemists between 1930 and 1960, spectrometers, and more. (shrink)

For decades, nursing as a discipline has tried to establish itself within the socio‐professional and the socio‐political arenas. To date, several theorists have attempted to thoroughly define the essence (ontology) of nursing while others have proposed means (syntax) to achieve this ‘collective’ objective. Considering that this preoccupation, rooted in essentialism, is pervasive in the nursing literature, our claim is that these quests should be criticized because they impede innovative and transdisciplinary approaches to nursing theory. Our criticism includes the perspective supported (...) by the so‐called ‘postmodern nursing theorists’. We argue that the oeuvre of some nursing postmodern scholars is as prescriptive and linear as the ones they critique. Like it was done before, the discourse of these thinkers perpetuates the status quo by excluding alternative forms of knowledge that cross the boundaries of the discipline of nursing. Using the work of Deleuze and Guattari, this paper proposes an alternative way to conceive the development of nursing knowledge, which, we think, could represent an alternative way to explore the discipline of nursing. (shrink)

Morality and the invention of feminine desire -- Sexuality versus recognition : feminine desire in the ethical order -- The purest poem : Heidegger's Antigone -- From Oedipus to Antigone : revisiting the question of feminine desire -- Family politics/family ethics : Butler, Lacan, and the thing beyond the object.

This popular reader has been vastly updated with ten stimulating new selections on the natural and the social sciences: feminism; postmodernism, relativism, and science; confirmation, acceptance, and theory; explanatory unification; and science and values. Retaining the best essays from the previous editions, the editors have added important new pieces to maintain this influential text's relevance.

Featuring nine new articles chosen by coeditor Steven M. Cahn, the third edition of E. D. Klemke's The Meaning of Life offers twenty-two insightful selections that explore this fascinating topic. The essays are primarily by philosophers but also include materials from literary figures and religious thinkers. As in previous editions, the readings are organized around three themes. In Part I the articles defend the view that without faith in God, life has no meaning or purpose. In Part II the selections (...) oppose this claim, defending instead a nontheistic, humanistic alternative--that life can have meaning even in the absence of theistic commitment. In Part III the contributors ask whether the question of the meaning of life is itself meaningful. The third edition adds substantial essays by Moritz Schlick, Joel Feinberg, and John Kekes as well as selections from the writings of Louis P. Pojman, Emil L. Fackenheim, Robert Nozick, Susan Wolf, and Steven M. Cahn. The only anthology of its kind, The Meaning of Life: A Reader, Third Edition, is ideal for courses in introduction to philosophy, human nature, and the meaning of life. It also offers general readers an accessible and stimulating introduction to the subject. (shrink)

Utilitarianism has an apparent pedigree when it comes to animal welfare. It supports the view that animal welfare matters just as much as human welfare. And many utilitarians support and oppose various practices in line with more mainstream concern over animal welfare, such as that we should not kill animals for food or other uses, and that we ought not to torture animals for fun. This relationship has come under tension from many directions. The aim of this article is to (...) add further considerations in support of that tension. I suggest three ways in which utilitarianism comes significantly apart from mainstream concerns with animal welfare. First, utilitarianism opposes animal cruelty only when it offers an inefficient ratio of pleasure to pain; while this may be true of eating animal products, it is not obviously true of other abuses. Second, utilitarianism faces a familiar problem of the inefficacy of individual decisions; I consider a common response to this worry, and offer further concerns. Finally, the common utilitarian argument against animal cruelty ignores various pleasures that humans may get from the superior status that a structure supporting exploitation confers. (shrink)

Ineffability, method, and ontology, by G. Bergmann.--The glory and the misery of Ludwig Wittgenstein, by G. Bergmann.--Stenius on the Tractatus, by G. Bergmann.--Naming and saying, by W. Sellars.--The ontology of Wittgenstein's Tractatus, by E. D. Klemke.--Material properties in the Tractatus, by H. Hochberg.--Wittgenstein's pantheism: a new light on the ontology of the Tractatus, by N. Garver.--Science and metaphysics: a Wittgensteinian interpretation, by H. Petrie.--Wittgenstein on private languages, by C. L. Hardin.--Wittgenstein on private language, by N. Garver.--Wittgenstein and private languages, by (...) W. Todd.--The private-language argument, by H.-N. Castañeda.--Wittgenstein on privacy, by J. W. Cook.--"Forms of life" in Wittgenstein's Philosophical investigations, by J. F. M. Hunter.--Privacy and language, by M. S. Gram.--On language games and forms of life, by F. Zabeeh.--Wittgenstein on meaning and use, by J. F. M. Hunter.--Wittgenstein on phenomenalism, skepticism, and criteria, by A. Oldenquist.--Tractarian reflections on saying and showing, by D. W. Stampe.--Wittgenstein and logical necessity, by B. Stroud.--Negation and generality, by H. Hochberg.--Facts, possibilities, and essences in the Tractatus, by H. Hochberg.--Arithmetic and propositional form in Wittgenstein's Tractatus, by H. Hochberg.--Selected bibliography (p. 543-546). (shrink)

This book is an examination of the philosophy of G.E. Moore, one of the foremost Anglo-American, analytic philosophers of the twentieth century. It focuses on Moore's epistemological writings and aims to present an exhaustive overview of Moore's work on analytic epistemology. This book seeks to redress an imbalance in analytic philosophy by making a case for the relevance of analytically oriented historical studies to contemporary problems.

This book defends Christian nurture and education against the frequently made charge of indoctrination. It argues that Christian education is fully compatible with a liberal education.